Away We Go (2009)

Not sure if this technically classifies as a rom-com, but its a cute story that follows the “weird” or eclectic couple of John Krasinski and Maya Rudolph who were both great as the quirky pregnant couple grappling with impending parenthood. Also starring Allison Janney (one of the greatest character actors), Catherine O’Hara, Jeff Daniels, Jim Gaffigan, and Maggie Gyllenhaal amongst a host of other familiar faces. Currently streaming on Starz.